Estimation of Ursolic Acid in Bauhinia racemosa Lam. by High-performance thin Layer Chromatography Method
Published: 2024-11-30
Page: 307-314
Issue: 2024 - Volume 7 [Issue 2]
Ankit Yadav *
S.V. K. M’s Mithibai College of Arts, Chauhan Institute of Science & Amrutben Jivanlal College of Commerce and Economics (Autonomous), Affiliated to University of Mumbai, Vile-Parle (West), Mumbai 400056, India.
Meenakshi Vaidya
S.V. K. M’s Mithibai College of Arts, Chauhan Institute of Science & Amrutben Jivanlal College of Commerce and Economics (Autonomous), Affiliated to University of Mumbai, Vile-Parle (West), Mumbai 400056, India.
*Author to whom correspondence should be addressed.
Abstract
Plants have been utilized since ancient times to cure and manage a variety of diseases. Their capacity to heal or prevent ailments is emanates from the presence of various phytochemicals such as alkaloids, flavonoids, glycosides, terpenoids, steroids, tannins, phenols, etc. Pentacyclic triterpenoids have attracted the interest of researchers due to their diverse pharmacological activities. One of the Pentacyclic triterpenoids is Ursolic acid (UA) with significant biological effects, including anti-inflammatory, anticancer, antidiabetic, antioxidant, and antibacterial properties. Bauhinia racemosa Lam. is used in folk medicines for the treatment of various disorders. In the present work, a subtle HPTLC method has been developed for determination of Ursolic acid in Bauhinia racemosa Lam. The demonstrated method is simple, rapid, accurate and can be used for routine qualitative testing.
Keywords: Secondary metabolite, pentacyclic triterpenoids, Ursolic acid, Bauhinia racemosa Lam, HPTLC