Screening for Pharmacological Compounds and Antioxidant Activity of Hedychium coronarium J. Koenig
Published: 2021-05-12
Page: 225-238
Issue: 2021 - Volume 4 [Issue 1]
Ezekwe Ahamefula Sunday *
1Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Rivers State University, Nkpolu Oroworukwo, Port Harcourt, Nigeria.
Nwadike Constance Nnedimma
Department of Medical Laboratory Science, Imo State University, Owerri, Nigeria.
Wokocha Gift Peter
1Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Rivers State University, Nkpolu Oroworukwo, Port Harcourt, Nigeria.
George Boma Orlando
1Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Rivers State University, Nkpolu Oroworukwo, Port Harcourt, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Screening for pharmacological compounds and antioxidants activity of Hedychium coronarium leaf sample was undertaking. Phytochemicals, gas chromatography-mass spectrometry (GC-MS) analysis and antioxidant activity of the leaf sample were evaluated using standard methods. The result of phytochemical screening revealed the presence of alkaloids, flavonoids, cardiac glycosides, phlobatannins, and proteins. The GC-MS analysis of the leaf extract revealed the presence of indole, phytol and other important compounds of interest. The leaf extract also exhibited better radical scavenging activity against the control in the present study. The bulk of the phytochemicals found present and some of the compounds revealed by GC-MS analysis which are biologically active with physiological activities, could be behind the antioxidant activity of the leaf sample. They could as well be responsible for the pharmacological benefits derived from the leaf of H. coronarium. This study has revealed the pharmacological compounds and antioxidant activity of H. coronarium leaf sample.
Keywords: Radical scavenging activity, hedychium coronarium, phytochemicals, proteins